{"product_id":"coveram_5-_5_mg_tab_30_s","title":"كوفيرام 5\/ 5 ملغ قرص 30 قرص","description":"\u003ch2\u003e\u003cspan\u003e\u003cstrong\u003eCoveram 5 mg \/ 5 mg 30 Tablets\u003c\/strong\u003e\u003c\/span\u003e\u003c\/h2\u003e\n\u003cp\u003e\u003cspan\u003eCoveram contain Amlodipine + perindopril arginine.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003eAmlodipine a dihydropyridine Calcium-Channel Blocker which blocks the cellular influx of calcium ions that is responsible for maintaining the plateau phase of the action potential in the myocardial muscles thus reducing the strength of contractility and cardiovascular tone.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003ePerindopril is an angiotensin converting enzyme (ACE) inhibitor that inhibits the conversion of angiotensin I to angiotensin II by blocking the activity of the converting enzyme. The inhibition of ACE will result in decreased concentrations of Angiotensin II which will then result in decreased vasoconstriction activity because Angiotensin II receptors are deactivated. It also results in decreased water retention because aldosterone production is terminated.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eActive ingredients:\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eAmlodipine, Perindopril Arginine.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eIndications:\u003c\/strong\u003e\u003cbr\u003e\u003cstrong\u003eCoveram tablets used for:\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003e• Hypertension.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e• Angina.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eHow to use:\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003eTake coveram as per as direction of doctor.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eSide effects of coveram:\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003e• Headache.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e• Dizziness.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e• Hypotension.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e• Palpitations.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eCautions:\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003e• Severe hepatic impairment.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e• May be used coveram tablets with patients with renal impairment at normal doses.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e• Increase the dose with elderly patients must take place with care.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eInteractions of Coveram:\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003e• Grapefruit Juice: Increases plasma concentration of the drug.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e• Sildenafil: enhanced hypotensive effect of the drug when given with Sildenafil.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e• Simvastatin: increases the risk of myopathy when used with the drug.\u003c\/span\u003e\u003cbr\u003e\u003cspan\u003e• Clopidogrel: the drug may decreases clopidogrel effect.\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cstrong\u003eQuantity:\u003c\/strong\u003e\u003cbr\u003e\u003cspan\u003e30 Tabs\u003c\/span\u003e\u003cbr\u003e\u003cbr\u003e\u003cspan\u003eStore at room temperature\u003c\/span\u003e\u003c\/p\u003e","brand":"Nabd pharmacy","offers":[{"title":"Default Title","offer_id":45571989831851,"sku":"0230132","price":5.56,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0649\/7127\/6459\/files\/00_42787199-ccd2-4fd0-9cfe-1549dd244526.jpg?v=1760418285","url":"https:\/\/alavenuepharmacy.com\/products\/coveram_5-_5_mg_tab_30_s","provider":"Avenue pharmacy","version":"1.0","type":"link"}