{"product_id":"coveram_10-_5_mg_tab_30_s","title":"كوفيرام 10\/ 5 ملغ قرص 30 قرص","description":"\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eCoveram 10 mg \/ 5 mg 30 Tablets\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eAmlodipine + perindopril arginine\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eAmlodipine a dihydropyridine Calcium-Channel Blocker which blocks the cellular influx of calcium ions that is responsible for maintaining the plateau phase of the action potential in the myocardial muscles thus reducing the strength of contractility and cardiovascular tone.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003ePerindopril is an angiotensin converting enzyme (ACE) inhibitor that inhibits the conversion of angiotensin I to angiotensin II by blocking the activity of the converting enzyme. The inhibition of ACE will result in decreased concentrations of Angiotensin II which will then result in decreased vasoconstriction activity because Angiotensin II receptorsare deactivated. It also results in decreased water retention because aldosterone production is terminated.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eIndications:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e• Hypertension.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e• Angina.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eHow to store:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eKeep at room temperature.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003ePoints of interest:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e• This medication may cause drowsiness and it may persist the following day, do not drive or operate machinery until you know how it affects you.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e• Try to take your medication at the same time every day.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003e\u003cbr\u003eHow to use:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eAs per as direction of doctor.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003e\u003cbr\u003eActive Ingredients:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003eAmlodipine , Perindopril Arginine.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003e\u003cbr\u003eSide effects:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e• Headache.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e• Dizziness.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e• Hypotension.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e• Palpitations.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eCautions:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e• Severe hepatic impairment.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e• May be used with patients with renal impairment at normal doses.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e• Increase the dose with elderly patients must take place with care.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003eInteractions:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e• Grapefruit Juice: Increases plasma concentration of the drug.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e• Sildenafil: enhanced hypotensive effect of the drug when given with Sildenafil.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e• Simvastatin: increases the risk of myopathy when used with the drug.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e• Clopidogrel: the drug may decreases clopidogrel effect.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e\u003cstrong\u003e\u003cbr\u003eQuantity:\u003c\/strong\u003e\u003c\/span\u003e\u003c\/p\u003e\n\u003cp\u003e\u003cspan\u003e30 Tablets.\u003c\/span\u003e\u003c\/p\u003e","brand":"Nabd pharmacy","offers":[{"title":"Default Title","offer_id":45571989635243,"sku":"0230133","price":9.09,"currency_code":"KWD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0649\/7127\/6459\/files\/018_16fe0afa-8a26-4bfe-8651-489327b94961.jpg?v=1760423840","url":"https:\/\/alavenuepharmacy.com\/products\/coveram_10-_5_mg_tab_30_s","provider":"Avenue pharmacy","version":"1.0","type":"link"}